Merck Manual


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Merck and The Merck Manuals

Merck is committed to bringing out the best in medicine. As part of that effort, Merck has created The Merck Manuals, a series of healthcare books for medical professionals and consumers. As a service to the community, the content of The Manuals is now available in enhanced online versions. The Merck Manual Online is updated periodically with new information, and contains photographs, and audio and video material not present in the print versions.

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Editors of The Merck Manual Online

Robert S. Porter, MD, Editor-in-chief

Justin L. Kaplan, MD, Senior Assistant Editor

Editorial Board of The Merck Manual Online

Richard K. Albert, MD

Glenn D. Braunstein, MD

Sidney Cohen, MD

Eugene P. Frenkel, MD

Susan L. Hendrix, DO

Robert M.A. Hirschfeld, MD

Michael Jacewicz, MD

Matthew E. Levison, MD

James Jeffrey Malatack, MD

Brian F. Mandell, MD, PhD

David A. Spain, MD

Paul H. Tanser, MD

Eva M. Vivian, PharmD

Michael R. Wasserman, MD



Important: The authors, reviewers, and editors of this book have made extensive efforts to ensure that treatments, drugs, and dosage regimens are accurate and conform to the standards accepted at the time of publication. However, constant changes in information resulting from continuing research and clinical experience, reasonable differences in opinions among authorities, unique aspects of individual clinical situations, and the possibility of human error in preparing such an extensive text require that the reader exercise individual judgment when making a clinical decision and, if necessary, consult and compare information from other sources. In particular, the reader is advised to check the product information provided by the manufacturer of a drug product before prescribing or administering it, especially if the drug is unfamiliar or is used infrequently.


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